Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). It blocks the hydrolysis of 9-PAHSA with an IC50 value of 0.57 μM. JJH260 also inhibits the novel FAHFA hydrolase androgen-dependent TFPI-regulating protein (ADTRP; IC50 = 8.5 μM), as well as the serine hydrolase ABHD6 and the lysophospholipases LYPLA1 and LYPLA2. JJH260 inhibits the FAHFA hydrolase activity of LNCaP and T cell lysates and intact cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 296.00 | |
1 mg | 35 days | $ 575.00 | |
5 mg | 35 days | $ 2,700.00 |
Description | JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). It blocks the hydrolysis of 9-PAHSA with an IC50 value of 0.57 μM. JJH260 also inhibits the novel FAHFA hydrolase androgen-dependent TFPI-regulating protein (ADTRP; IC50 = 8.5 μM), as well as the serine hydrolase ABHD6 and the lysophospholipases LYPLA1 and LYPLA2. JJH260 inhibits the FAHFA hydrolase activity of LNCaP and T cell lysates and intact cells. |
Synonyms | JJH260 |
Molecular Weight | 568.06 |
Formula | C29H34ClN5O5 |
CAS No. | 1831135-30-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 1 mg/mL
DMF:PBS(pH7.2) (1:2): 0.33 mg/mL
You can also refer to dose conversion for different animals. More
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JJH260 1831135-30-8 JJH-260 JJH 260 inhibitor inhibit