Powder: -20°C for 3 years | In solvent: -80°C for 1 year
hAChE-IN-2, a potent inhibitor of human acetylcholinesterase (hAChE), exhibits an inhibitory concentration 50 (IC50) of 0.71 μM and additionally impedes tau-oligomerization with an effective concentration 50 (EC50) of 2.21 μM, demonstrating neuroprotective activity [1].
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Description | hAChE-IN-2, a potent inhibitor of human acetylcholinesterase (hAChE), exhibits an inhibitory concentration 50 (IC50) of 0.71 μM and additionally impedes tau-oligomerization with an effective concentration 50 (EC50) of 2.21 μM, demonstrating neuroprotective activity [1]. |
Targets&IC50 | hAChE:0.71 μM |
In vitro | Compound 21 (hAChE-IN-2), at concentrations ranging from 1-10 μM, exhibited neuroprotective activity in SH-SY5Y cells transfected with wild-type tau [1]. |
Molecular Weight | 394.44 |
Formula | C22H23FN4O2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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