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Anti-MST1 Antibody (6Z738) is a Mouse antibody targeting MST1. Anti-MST1 Antibody (6Z738) can be used in ELISA(Det).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $69 | 7-10 days | |
100 μL | $198 | 7-10 days |
Description | Anti-MST1 Antibody (6Z738) is a Mouse antibody targeting MST1. Anti-MST1 Antibody (6Z738) can be used in ELISA(Det). |
Alias | YSK3, TIIAC, serine/threonine kinase 4, MST1, KRS2 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 6Z738 |
Reactivity | Human |
Application | ELISA(Det) |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human STK4 / MST1 (rh STK4 / MST1; TMPY-04398; Q13043-1; Glu2-Phe487). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially regulates TLR3/4/9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated Hepatocellular carcinoma (HCC). STK4 has potential as a diagnostic biomarker and therapeutic target for inflammation-induced HCC. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human STK4 / MST1 Protein (TMPY-04398) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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