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Anti-CD40 Ligand Antibody (8X489)
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Catalog No. TMAY-00513
Alias TRAP, Tnfsf5, T-BAM, Ly-62, Ly62, IMD3, Igm, HIGM1, gp39, CD40-L, Cd40l, CD40 ligand, CD154
Anti-CD40 Ligand Antibody (8X489) is a Mouse antibody targeting CD40 Ligand. Anti-CD40 Ligand Antibody (8X489) can be used in ELISA.
Anti-CD40 Ligand Antibody (8X489)
Anti-CD40 Ligand Antibody (8X489)
😃Good
Catalog No. TMAY-00513Alias TRAP, Tnfsf5, T-BAM, Ly-62, Ly62, IMD3, Igm, HIGM1, gp39, CD40-L, Cd40l, CD40 ligand, CD154
Anti-CD40 Ligand Antibody (8X489) is a Mouse antibody targeting CD40 Ligand. Anti-CD40 Ligand Antibody (8X489) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-CD40 Ligand Antibody (8X489) is a Mouse antibody targeting CD40 Ligand. Anti-CD40 Ligand Antibody (8X489) can be used in ELISA. |
| Alias | TRAP, Tnfsf5, T-BAM, Ly-62, Ly62, IMD3, Igm, HIGM1, gp39, CD40-L, Cd40l, CD40 ligand, CD154 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 8X489 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD40L / CD154 / TNFSF5 (rh CD40L / CD154 / TNFSF5; TMPY-01758; NP_000065.1; Glu 108-Leu 261). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD154, also known as CD40 ligand or CD40L, is a member of the TNF superfamily. While CD154 was originally found on T cell surface, its expression has since been found on a wide variety of cells, including platelets, mast cells, macrophages and NK cells. CD154's ability is achieved through binding to the CD40 on antigen-presenting cells (APC). In the macrophage cells, the primary signal for activation is IFN-γ from Th1 type CD4 T cells. The secondary signal is CD40L on the T cell, which interacting with the CD40 molecules, helping increase the level of activation.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CD40L / CD154 / TNFSF5 protein (TMPY-01758) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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