Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Prostacyclin (PGI2) is a cyclooxygenase metabolite with antithrombotic properties found in vascular endothelial cells. The half-life is short both in vivo and in vitro, ranging from 30 seconds to a few minutes. CG 4305 is a stable carbacyclic analog of PGI2 that inhibits ADP-induced platelet aggregation 25% at a concentration of 50 nM. Doses of 10 mg/kg (oral) or 1 mg/kg (intraduodenal) have been shown to prevent rabbit carotid artery thrombosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 35 days | $ 253.00 | |
500 μg | 35 days | $ 1,120.00 | |
1 mg | 35 days | $ 1,990.00 |
Description | Prostacyclin (PGI2) is a cyclooxygenase metabolite with antithrombotic properties found in vascular endothelial cells. The half-life is short both in vivo and in vitro, ranging from 30 seconds to a few minutes. CG 4305 is a stable carbacyclic analog of PGI2 that inhibits ADP-induced platelet aggregation 25% at a concentration of 50 nM. Doses of 10 mg/kg (oral) or 1 mg/kg (intraduodenal) have been shown to prevent rabbit carotid artery thrombosis. |
Molecular Weight | N/A |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL
Ethanol: 3 mg/mL
DMSO:PBS (pH 7.2) (1:10): 0.1 mg/mL
DMF: 5 mg/mL
You can also refer to dose conversion for different animals. More
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CG 4305 CG-4305 CG4305 inhibitor inhibit