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9-Nitrooleate

Name: 9-Nitrooleate
Brand: TargetMol
SKU: T36830
Rating: 4.5 (1 reviews)

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9-Nitrooleate is a nitrated fatty acid and a derivative of oleic acid modified by nitration, with potential applications in the research of vascular-related diseases.

Cas No. 875685-44-2

Pack Size	Price	USA Stock	Global Stock
50 μg	$113	35 days	35 days
100 μg	$178	35 days	35 days
500 μg	$748	35 days	35 days
1 mg	$1,300	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Liquid

Color:Transparent

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Product Introduction

Bioactivity

Description

9-Nitrooleate is a nitrated fatty acid and a derivative of oleic acid modified by nitration, with potential applications in the research of vascular-related diseases.

In vitro

Methods: This review summarizes the sources of 9-Nitrooleate and the anti-inflammatory and vascular protective mechanisms of nitro fatty acids, focusing on their signaling pathways and effects in cardiovascular disease models.
Results: 9-Nitrooleate is a nitro fatty acid generated by the reaction of nitric oxide (NO) with unsaturated fatty acids under oxidative stress conditions. This type of substance can exert anti-inflammatory and vascular protective effects by activating the PPARγ pathway or non-PPAR pathways, and can antagonize angiotensin II receptors in cardiovascular disease models, thereby improving hypertension.

Chemical Properties

Molecular Weight	327.46
Formula	C₁₈H₃₃NO₄
Cas No.	875685-44-2
Smiles	OC(CCCCCCC/C([N+]([O-])=O)=C\CCCCCCCC)=O
Relative Density.	no data available

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	Ethanol: < 1 mg/mL (insoluble), Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.