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Anti-IL-18 Antibody (6L460)
😃Good
Catalog No. TMAH-00614
Alias Interleukin 1, IL-1g, IL-1F4, IL1F4, IL-18, IL18, IL-1 γ, IL-1 gamma, IGIF
Anti-IL-18 Antibody (6L460) is an antibody targeting IL-18. Anti-IL-18 Antibody (6L460) can be used in ELISA, FC.
Anti-IL-18 Antibody (6L460)
Anti-IL-18 Antibody (6L460)
😃Good
Catalog No. TMAH-00614Alias Interleukin 1, IL-1g, IL-1F4, IL1F4, IL-18, IL18, IL-1 γ, IL-1 gamma, IGIF
Anti-IL-18 Antibody (6L460) is an antibody targeting IL-18. Anti-IL-18 Antibody (6L460) can be used in ELISA, FC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | 198 € | 7-10 days | |
| 100 μL | 329 € | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Monoclonal Application: ELISA, FC Reactivity: Human |
| Alias | Interleukin 1, IL-1g, IL-1F4, IL1F4, IL-18, IL18, IL-1 γ, IL-1 gamma, IGIF |
| Ig Type | hIgG1 |
| Clone | 6L460 |
| Reactivity | Human |
| Verified Activity | Overlay Peak curve showing A549 cells stained with TMAH-00614 (red line) at 1:200. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Human IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was human IgG (1ug/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| Application | ELISA, FC |
| Recommended Dose | FC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Secreted. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human IL18 Protein |
| Antigen Species | Human |
| Gene ID | 3606 |
| Uniprot ID | |
| Biology Area | Cancer, Immunology, Metabolism |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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