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Anti-THSD1 Antibody (5V688) is a Rabbit antibody targeting THSD1. Anti-THSD1 Antibody (5V688) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-THSD1 Antibody (5V688) is a Rabbit antibody targeting THSD1. Anti-THSD1 Antibody (5V688) can be used in ELISA. |
Alias | Tmtsp, thrombospondin type 1 domain containing 1, 4833423O18Rik |
Ig Type | Monoclonal Rabbit IgG |
Clone | 5V688 |
Reactivity | Mouse |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse THSD1 (rM THSD1; TMPY-01484; NP_062522.1; Met 1-Asn 412). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is a multi-domain, multi-functional glycoprotein synthesized by many cells. Matricellular THSD1 modulates cell adhesion and proliferation. It is involved in angiogenesis, inflammation, wound healing and cancer. In vitro, nanomolar concentrations of Thrombospondin-1 are required to alter endothelial and vascular smooth muscle cell adhesion, proliferation, motility, and survival. As a major platelet protein, for a long time it was postulated to control hemostasis via platelet aggregate stabilization. THSD1 is a potent angiogenesis inhibitor, and down-regulation of THSD1 has been suggested to alter tumor growth by modulating angiogenesis in a variety of tumor types. |
Conjucates | Unconjugated |
Immunogen | Recombinant Mouse THSD1 protein (TMPY-01484) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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