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RC-106
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Catalog No. T87296Cas No. 1346216-50-9
RC-106, a proteasome inhibitor (IC50: 35 μM) and Sigma receptor modulator, exhibits anticancer activity and antiproliferative effects against cancer cells, including glioblastoma (GB) and multiple myeloma (MM) [1].
RC-106
😃Good
Catalog No. T87296Cas No. 1346216-50-9
RC-106, a proteasome inhibitor (IC50: 35 μM) and Sigma receptor modulator, exhibits anticancer activity and antiproliferative effects against cancer cells, including glioblastoma (GB) and multiple myeloma (MM) [1].
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | RC-106, a proteasome inhibitor (IC50: 35 μM) and Sigma receptor modulator, exhibits anticancer activity and antiproliferative effects against cancer cells, including glioblastoma (GB) and multiple myeloma (MM) [1]. |
| In vitro | RC-106, when administered at a concentration of 60 μM for 24 hours, was found to inhibit the viability of cancer cells [1]. In a cell viability assay [1] using U87-MG cells, RC-106 demonstrated moderate activity. Specifically, at concentrations of 40 and 60 μM over an incubation period of 24 hours, it notably reduced cell viability to 34% at the higher concentration. |
| Molecular Weight | 355.52 |
| Formula | C26H29N |
| Cas No. | 1346216-50-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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