keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mad1 (6-21) is a peptide fragment derived from the Mad1 protein, specifically encompassing residues 6 to 21. This fragment exhibits binding affinity towards the mammalian Sin3A PAH2 domain, with a Kd value of approximately 29 nM.
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Description | Mad1 (6-21) is a peptide fragment derived from the Mad1 protein, specifically encompassing residues 6 to 21. This fragment exhibits binding affinity towards the mammalian Sin3A PAH2 domain, with a Kd value of approximately 29 nM. |
In vitro | The PAH2 domain of mSin3A forms a left-handed, four-helix bundle with residues from all helices and turn regions creating a compact domain featuring a significant hydrophobic core. Helices α1 and α2 generate a deep hydrophobic pocket, serving as the main interaction site for the Mad1 (6-21) peptide. This Mad1 (6-21) peptide assumes an amphipathic α-helical structure upon binding, predominantly engaging with PAH2 through its nonpolar surface[1]. |
Synonyms | Mad1 (6-21) |
Molecular Weight | 1966.31 |
Formula | C84H140N24O26S2 |
CAS No. | 880150-82-3 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Mad1 (6-21) 880150-82-3 Mad1 (621) Mad-1 (6-21) Mad1 Mad1 (6 21) inhibitor inhibit