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Anti-Fibronectin Antibody (8U82)
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Catalog No. TMAH-00445
Alias FN1, Fibronectin
Anti-Fibronectin Antibody (8U82) is an antibody targeting Fibronectin. Anti-Fibronectin Antibody (8U82) can be used in ELISA, IHC.
Anti-Fibronectin Antibody (8U82)
Anti-Fibronectin Antibody (8U82)
😃Good
Catalog No. TMAH-00445Alias FN1, Fibronectin
Anti-Fibronectin Antibody (8U82) is an antibody targeting Fibronectin. Anti-Fibronectin Antibody (8U82) can be used in ELISA, IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $348 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Fibronectin Antibody (8U82) is an antibody targeting Fibronectin. Anti-Fibronectin Antibody (8U82) can be used in ELISA, IHC. |
| Alias | FN1, Fibronectin |
| Ig Type | Rabbit IgG |
| Clone | 8U82 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-00445 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Fibronectin |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Cardiovascular, Developmental biology, Signal transduction, Stem cells |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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