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Pararosaniline hydrochloride

(Synonyms: Basic red 9, 4,4'-((4-Iminocyclohexa-2,5-dien-1-ylidene)methylene)dianiline hydrochloride) Copy Product Info
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Synonyms: Basic red 9, 4,4'-((4-Iminocyclohexa-2,5-dien-1-ylidene)methylene)dianiline hydrochloride

Catalog No. T64740 Copy Product Info
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4,4'-((4-Iminocyclohexa-2,5-dien-1-ylidene)methylene)dianiline hydrochloride is a useful organic compound for life science research
Pararosaniline hydrochloride
Cas No. 569-61-9
Pack SizePriceUSA StockGlobal StockQuantity
10 g$317-10 days7-10 days
1 mL x 10 mM (in DMSO)$357-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
4,4'-((4-Iminocyclohexa-2,5-dien-1-ylidene)methylene)dianiline hydrochloride is a useful organic compound for life science research
In vitro
Method: C.I. Basic Red 9 monohydrochloride was tested in Salmonella typhimurium TA98, TA100, TA1535 and TA1537 with and without metabolic activation, in L5178Y/TK mouse lymphoma cells, and in Chinese hamster ovary sister-chromatid-exchange and chromosomal-aberration assays.[1]
Rresult: The compound was mutagenic in TA98 and TA100 and induced mutations in L5178Y/TK cells. It was negative in TA1535 and TA1537 and did not induce chromosomal aberrations in Chinese hamster ovary cells; sister-chromatid exchange increased under metabolic-activation conditions.[1]
In vivo
Method: Groups of 50 male and 50 female F344/N rats and B6C3F1 mice received pararosaniline hydrochloride in feed for 103 weeks. Male rats received 0, 1000 or 2000 ppm; female rats and mice received 0, 500 or 1000 ppm.[1]
Rresult: Long-term dietary exposure produced clear evidence of carcinogenic activity in male and female F344/N rats and B6C3F1 mice, with increased incidences of treatment-related neoplasms.[1]
SynonymsBasic red 9, 4,4'-((4-Iminocyclohexa-2,5-dien-1-ylidene)methylene)dianiline hydrochloride
Chemical Properties
Molecular Weight323.82
FormulaC19H18ClN3
Cas No.569-61-9
SmilesCl.N=C1C=CC(C=C1)=C(C2=CC=C(N)C=C2)C3=CC=C(N)C=C3
Storage & Solubility Information
StorageKeep away from moisture,Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (247.05 mM), Sonication is recommended.
H2O: 7.568 mg/mL (23.37 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.0881 mL15.4407 mL30.8814 mL154.4068 mL
5 mM0.6176 mL3.0881 mL6.1763 mL30.8814 mL
10 mM0.3088 mL1.5441 mL3.0881 mL15.4407 mL
20 mM0.1544 mL0.7720 mL1.5441 mL7.7203 mL
DMSO
1mg5mg10mg50mg
50 mM0.0618 mL0.3088 mL0.6176 mL3.0881 mL
100 mM0.0309 mL0.1544 mL0.3088 mL1.5441 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
µL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Pararosaniline hydrochloride chemical structure | Pararosaniline hydrochloride in vivo | Pararosaniline hydrochloride in vitro | Pararosaniline hydrochloride formula | Pararosaniline hydrochloride molecular weight