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Anti-B7-1 Antibody (2N313)
🥰Excellent
Catalog No. TMAY-03298
Anti-B7-1 Antibody (2N313) is a Rabbit antibody targeting B7-1. Anti-B7-1 Antibody (2N313) can be used in FCM.
Anti-B7-1 Antibody (2N313)
Anti-B7-1 Antibody (2N313)
🥰Excellent
Catalog No. TMAY-03298
Anti-B7-1 Antibody (2N313) is a Rabbit antibody targeting B7-1. Anti-B7-1 Antibody (2N313) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-B7-1 Antibody (2N313) is a Rabbit antibody targeting B7-1. Anti-B7-1 Antibody (2N313) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2N313 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse CD80 expression on LPS-stimulated BABL/c splenocytes. Cells were stained with purified anti-Mouse CD80, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD80/B7-1 (rM CD80/B7-1; TMPY-02307; Q00609-1; Met1-Lys245). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Mouse CD80/B7-1 Protein (TMPY-02307) |
| Antigen Species | Mouse |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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