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LUF5771 is a highly potent allosteric inhibitor of recombinant luteinizing hormone (recLH) and Org 43553. It exhibits partial activation of the LH receptor with low efficacy [1].

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $58 | 5 days | 5 days |
| Description | LUF5771 is a highly potent allosteric inhibitor of recombinant luteinizing hormone (recLH) and Org 43553. It exhibits partial activation of the LH receptor with low efficacy [1]. |
| In vitro | LUF5771 (1 μM or 10 μM) allosteric inhibition is concentration-dependent. LUF5771 significantly increases radioligand dissociation. LUF5771 probably binds to the seven transmembrane domain like Org 43553 does. LUF5771 (10 μM) alone is able to partially activate the LH receptor by 31±4% [1]. |
| Molecular Weight | 357.44 |
| Formula | C24H23NO2 |
| Cas No. | 1141802-49-4 |
| Smiles | O=C(NC1CCCC1)Oc1cc(cc(c1)-c1ccccc1)-c1ccccc1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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