Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WLB-89462 (Compound 20c) is a selective σ2 receptor ligand with a K i of 13 nM, exhibiting neuroprotective properties and the ability to ameliorate Aβ peptide-induced short-term memory impairment in rats. It possesses a favorable ADMET profile characterized by good solubility, absence of CYP inhibition, robust metabolic stability, high permeability, effective brain penetration, and substantial oral exposure in rodent models [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | WLB-89462 (Compound 20c) is a selective σ2 receptor ligand with a K i of 13 nM, exhibiting neuroprotective properties and the ability to ameliorate Aβ peptide-induced short-term memory impairment in rats. It possesses a favorable ADMET profile characterized by good solubility, absence of CYP inhibition, robust metabolic stability, high permeability, effective brain penetration, and substantial oral exposure in rodent models [1]. |
Molecular Weight | 399.49 |
Formula | C21H29N5O3 |
CAS No. | 2849471-75-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
WLB-89462 2849471-75-4 GPCR/G Protein Sigma receptor inhibitor inhibit