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Anti-SOD1 Antibody (3H501) (Synonyms: superoxide dismutase 1, soluble, SOD, IPOA, hSod1, homodimer, HEL-S-4...)

Catalog No. TMAY-02026 Copy Product Info
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Anti-SOD1 Antibody (3H501) is a Mouse antibody targeting SOD1. Anti-SOD1 Antibody (3H501) can be used in ELISA.

Anti-SOD1 Antibody (3H501)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02026
Synonyms superoxide dismutase 1, soluble, SOD, IPOA, hSod1, homodimer, HEL-S-44, ALS1, ALS

Anti-SOD1 Antibody (3H501) is a Mouse antibody targeting SOD1. Anti-SOD1 Antibody (3H501) can be used in ELISA.

Anti-SOD1 Antibody
(3H501)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SOD1 Antibody (3H501) is a Mouse antibody targeting SOD1. Anti-SOD1 Antibody (3H501) can be used in ELISA.
Synonymssuperoxide dismutase 1, soluble, SOD, IPOA, hSod1, homodimer, HEL-S-44, ALS1, ALS
Ig Type
Mouse IgG1
Clone
3H501
Reactivity
Human
Specificity
Human SOD1/Cu-Zn SOD
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SOD1/Cu-Zn SOD (rh SOD1/Cu-Zn SOD; TMPY-01585; NP_000445.1; Ala2-Gln154). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSOD1 belongs to the Cu-Zn superoxide dismutase family. It binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. SOD1 destroys radicals which are normally produced within the cells and which are toxic to biological systems. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1 (ALS1). ALS1 is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of cases leading to familial forms.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human SOD1/Cu-Zn SOD Protein (TMPY-01585)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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