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Sofituzumab vedotin (Synonyms: DMUC5754A)
Catalog No. T81133 Copy Product Info
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Sofituzumab vedotin (DMUC5754A) is an antibody-drug conjugate (ADC) comprising an anti-MUC16 antibody linked to monomethyl auristatin E (MMAE) via a protease-cleavable linker, utilized for cancer research [1].
Sofituzumab vedotin
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Catalog No. T81133
Synonyms DMUC5754A
Sofituzumab vedotin (DMUC5754A) is an antibody-drug conjugate (ADC) comprising an anti-MUC16 antibody linked to monomethyl auristatin E (MMAE) via a protease-cleavable linker, utilized for cancer research [1].
Sofituzumab vedotin
Cas No. 1418200-58-4
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $758 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $1,880 | 2-4 weeks | 2-4 weeks | |
| 10 mg | Preferential | 2-4 weeks | 2-4 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Sofituzumab vedotin (DMUC5754A) is an antibody-drug conjugate (ADC) comprising an anti-MUC16 antibody linked to monomethyl auristatin E (MMAE) via a protease-cleavable linker, utilized for cancer research [1]. |
| In vitro | Sofituzumab vedotin (DMUC5754A) is an antibody-drug conjugate (ADC) composed of a humanized IgG1 anti-MUC16 monoclonal antibody linked to the potent mitotic inhibitor MMAE via a protease-labile linker, maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl [2]. |
| In vivo | Sofituzumab vedotin (3A5-VC-MMAE; 2 and 2.8 mg/kg; IV; once weekly for 3 or 4 total doses) demonstrated robust antitumor activity in a human MUC16-expressing OVCAR-3 mouse xenograft model [3]. |
| Synonyms | DMUC5754A |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal, ADC |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | MMAE |
| Gene ID | |
| Uniprot ID | |
| Target | CA125/MUC16 |
| Cas No. | 1418200-58-4 |
| Isotype | IgG1 |
| Storage | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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