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D-Mannitol

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Catalog No. T0414Cas No. 69-65-8
Alias Osmitrol, Mannitol, Mannite

D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. D-Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.

D-Mannitol
Other Forms of D-Mannitol:

D-Mannitol

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Purity: 99.68%
Catalog No. T0414Alias Osmitrol, Mannitol, ManniteCas No. 69-65-8
D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. D-Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 mg$44In StockIn Stock
1 g$46In StockIn Stock
2 g$48In StockIn Stock
5 g$53-In Stock
10 g$68-In Stock
25 g$98-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.68%
Appearance:Solid
Color:White
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. D-Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
SynonymsOsmitrol, Mannitol, Mannite
Chemical Properties
Molecular Weight182.17
FormulaC6H14O6
Cas No.69-65-8
Smiles[C@H]([C@@H]([C@@H](CO)O)O)([C@@H](CO)O)O
Relative Density.1.52
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 35.71 mg/mL (196.03 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM5.4894 mL27.4469 mL54.8938 mL274.4689 mL
5 mM1.0979 mL5.4894 mL10.9788 mL54.8938 mL
10 mM0.5489 mL2.7447 mL5.4894 mL27.4469 mL
20 mM0.2745 mL1.3723 mL2.7447 mL13.7234 mL
50 mM0.1098 mL0.5489 mL1.0979 mL5.4894 mL
100 mM0.0549 mL0.2745 mL0.5489 mL2.7447 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MDHInhibitorinhibitEndogenousMetaboliteEndogenous MetaboliteD-MannitolDMannitolD MannitolApoptosis
Related Tags: buy D-Mannitol | purchase D-Mannitol | D-Mannitol cost | order D-Mannitol | D-Mannitol chemical structure | D-Mannitol formula | D-Mannitol molecular weight
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