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IDO inhibitor 1

Name: IDO inhibitor 1
Brand: TargetMol
SKU: T7660
Price: 91 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7660Cas No. 1204669-37-3

IDO inhibitor 1 is an potent inhibitor of indoleamine-2,3 dioxygenase (IDO) ( IC50 <100 nM).with potential immunomodulating and antineoplastic activities.

IDO inhibitor 1

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Purity: 99.80%

Catalog No. T7660Cas No. 1204669-37-3

IDO inhibitor 1 is an potent inhibitor of indoleamine-2,3 dioxygenase (IDO) ( IC50 <100 nM).with potential immunomodulating and antineoplastic activities.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$91	In Stock	In Stock
2 mg	$148	In Stock	In Stock
5 mg	$213	In Stock	In Stock
10 mg	$326	In Stock	In Stock
25 mg	$475	In Stock	In Stock
50 mg	$695	In Stock	In Stock
100 mg	$988	-	In Stock
500 mg	$1,980	-	In Stock
1 mL x 10 mM (in DMSO)	$245	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.80%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	IDO inhibitor 1 is an potent inhibitor of indoleamine-2,3 dioxygenase (IDO) ( IC50 <100 nM).with potential immunomodulating and antineoplastic activities.
Targets&IC50	IDO:<100 nM

Chemical Properties

Molecular Weight	438.23
Formula	C₁₁H₁₃BrFN₇O₄S
Cas No.	1204669-37-3
Smiles	NS(=O)(=O)NCCNc1nonc1/C(=N/O)Nc1ccc(F)c(Br)c1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (148.32 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2819 mL	11.4095 mL	22.8191 mL	114.0953 mL
5 mM	0.4564 mL	2.2819 mL	4.5638 mL	22.8191 mL
10 mM	0.2282 mL	1.1410 mL	2.2819 mL	11.4095 mL
20 mM	0.1141 mL	0.5705 mL	1.1410 mL	5.7048 mL
50 mM	0.0456 mL	0.2282 mL	0.4564 mL	2.2819 mL
100 mM	0.0228 mL	0.1141 mL	0.2282 mL	1.1410 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc