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TLX agonist 1

Name: TLX agonist 1
Brand: TargetMol
SKU: T7833
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T7833Cas No. 958323-31-4

TLX agonist 1 is an orphan nuclear receptor tailless (TLX, NR2E1) modulator

TLX agonist 1

🥰Excellent

Purity: 99.34%

Catalog No. T7833Cas No. 958323-31-4

TLX agonist 1 is an orphan nuclear receptor tailless (TLX, NR2E1) modulator

Pack Size	Price	Availability
1 mg	$31	In Stock
5 mg	$73	In Stock
10 mg	$113	In Stock
25 mg	$227	In Stock
50 mg	$341	In Stock
100 mg	$489	In Stock
200 mg	$679	In Stock
1 mL x 10 mM (in DMSO)	$80	In Stock

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Batch Information

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Purity:99.34%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

TLX agonist 1 is an orphan nuclear receptor tailless (TLX, NR2E1) modulator

Chemical Properties

Molecular Weight	374.48
Formula	C₂₃H₂₆N₄O
Cas No.	958323-31-4
Smiles	Cc1cc(nn1C)C(=O)N1CCN(CC1)C(c1ccccc1)c1ccccc1
Relative Density.	1.16 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 62.5 mg/mL (166.9 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.34 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6704 mL	13.3518 mL	26.7037 mL	133.5185 mL
5 mM	0.5341 mL	2.6704 mL	5.3407 mL	26.7037 mL
10 mM	0.2670 mL	1.3352 mL	2.6704 mL	13.3518 mL
20 mM	0.1335 mL	0.6676 mL	1.3352 mL	6.6759 mL
50 mM	0.0534 mL	0.2670 mL	0.5341 mL	2.6704 mL
100 mM	0.0267 mL	0.1335 mL	0.2670 mL	1.3352 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc