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Ketorolac

Name: Ketorolac
Brand: TargetMol
SKU: T21412
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21412Cas No. 74103-06-3

Alias Toradol, Sprix, Macril, Acuvail, Acular

Ketorolac (Acuvail) is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It acts by inhibiting the bodily synthesis of prostaglandins.

Ketorolac

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Purity: 99.68%

Catalog No. T21412Alias Toradol, Sprix, Macril, Acuvail, AcularCas No. 74103-06-3

Ketorolac (Acuvail) is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It acts by inhibiting the bodily synthesis of prostaglandins.

Pack Size	Price	Availability
100 mg	$35	In Stock
500 mg	$80	In Stock
1 g	$117	In Stock

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Batch Information

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Purity:99.68%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Ketorolac (Acuvail) is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It acts by inhibiting the bodily synthesis of prostaglandins.
Targets&IC50	COX-2:120 nM , COX-1:20 nM
Synonyms	Toradol, Sprix, Macril, Acuvail, Acular

Chemical Properties

Molecular Weight	255.27
Formula	C₁₅H₁₃NO₃
Cas No.	74103-06-3
Smiles	OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1
Relative Density.	1.398 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (176.28 mM), Sonication is recommended.

H2O: 70 mg/mL (274.22 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	3.9174 mL	19.5871 mL	39.1742 mL	195.8710 mL
5 mM	0.7835 mL	3.9174 mL	7.8348 mL	39.1742 mL
10 mM	0.3917 mL	1.9587 mL	3.9174 mL	19.5871 mL
20 mM	0.1959 mL	0.9794 mL	1.9587 mL	9.7936 mL
50 mM	0.0783 mL	0.3917 mL	0.7835 mL	3.9174 mL
100 mM	0.0392 mL	0.1959 mL	0.3917 mL	1.9587 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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