Shopping Cart
- Remove All
Your shopping cart is currently empty
RH1
🥰Excellent
Catalog No. T16740Cas No. 221635-42-3
Alias NSC 697726
RH1 (NSC 697726) is a bioreductive anticancer compound that exhibits dose-dependent biphasic effects in vitro, inducing apoptosis at higher doses and senescence at lower doses.
RH1
🥰Excellent
Purity: 99.15%
Catalog No. T16740Alias NSC 697726Cas No. 221635-42-3
RH1 (NSC 697726) is a bioreductive anticancer compound that exhibits dose-dependent biphasic effects in vitro, inducing apoptosis at higher doses and senescence at lower doses.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $197 | In Stock | |
| 5 mg | $446 | In Stock | |
| 10 mg | $718 | In Stock | |
| 25 mg | $1,450 | In Stock | |
| 50 mg | $1,980 | In Stock |
Add to Cart
Add to Quotation
Bulk & Custom
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
Questions
View MoreBatch Information
Select Batch
Purity:99.15%
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
| Description | RH1 (NSC 697726) is a bioreductive anticancer compound that exhibits dose-dependent biphasic effects in vitro, inducing apoptosis at higher doses and senescence at lower doses. |
| In vitro | RH1 causes apoptosis in NQ16 cells in a time- and concentration-dependent manner. Treatment of NQ16 cells with RH1 (50 and 100 nM) for 60 and 120 minutes resulted in a significant (p< 0.05) increase in cross-linked DNA [1]. |
| In vivo | RH1 exhibited dose-dependent antitumor activity against NQ16 tumors grown in thymus-free mice. A small dose of RH1 (0.1 mg/kg) also resulted in a significant reduction in tumor size in treated mice compared to controls. Treatment of mice with NQ16 tumors with RH1 (0.4 mg/kg and 0.2 mg/kg) resulted in a significant reduction in tumor size between the treated and control groups as early as 5 days after the end of the treatment period [2]. |
| Synonyms | NSC 697726 |
| Molecular Weight | 234.25 |
| Formula | C12H14N2O3 |
| Cas No. | 221635-42-3 |
| Smiles | O=C1C(=C(C(=O)C(=C1C)N2CC2)CO)N3CC3 |
| Relative Density. | no data available |
| Color | Red |
| Appearance | Solid |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | DMSO: 1 mg/mL (4.26 mM), Sonication and heating are recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
| |||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy RH1 | purchase RH1 | RH1 cost | order RH1 | RH1 chemical structure | RH1 in vivo | RH1 in vitro | RH1 formula | RH1 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.