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Arachidic acid

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Catalog No. T4775Cas No. 506-30-9
Alias Icosanoic Acid, eicosanoic acid

Arachidic acid (Icosanoic Acid) is a saturated fatty acid found naturally in fish and vegetable oils (such as those from peanuts). It can also be formed by the hydrogenation of arachidonic acid. Diets rich in saturated fatty acids, such as arachidic acid, are known to increase serum low-density lipoproteins resulting in high blood cholesterol levels.

Arachidic acid

Arachidic acid

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Purity: 98%
Catalog No. T4775Alias Icosanoic Acid, eicosanoic acidCas No. 506-30-9
Arachidic acid (Icosanoic Acid) is a saturated fatty acid found naturally in fish and vegetable oils (such as those from peanuts). It can also be formed by the hydrogenation of arachidonic acid. Diets rich in saturated fatty acids, such as arachidic acid, are known to increase serum low-density lipoproteins resulting in high blood cholesterol levels.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$31-In Stock
1 mL x 10 mM (in DMSO)$30-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98%
Appearance:Solid
Color:White
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Product Introduction

Arachidic acid AI Summary
Arachidic acid has exhibited antioxidant activity as assessed by formazan formation-induced absorbance changes at 25 ppm at 570 nm at 37°C for 6 hours using the MTT assay, showing a deltaA value of 0.25. It demonstrates the capability to displace ligands from PPAR subtypes - PPARδ, PPARγ, and PPARα with an IC50 value of 30000.0 nM for each receptor, indicating potential modulation of metabolic, inflammatory, and cell differentiation processes. Additionally, Arachidic acid acts as an antagonist at recombinant rat TRPV2 expressed in HEK293 cells, inhibiting LPC-induced and CBD-induced Ca2+ levels with IC50 values greater than 10000.0 nM, suggesting moderate to low potency. It shows significant inhibitory activity against electric eel Acetylcholinesterase (AChE) with an inhibition of 33.93% and an IC50 value of 12800.0 nM and exhibits moderate inhibitory activity against equine serum Butyrylcholinesterase (BuChE) with 4.67% inhibition. Further, Arachidic acid inhibits retinal reductase in Sprague-Dawley rat liver microsomes by 20% at 100 uM. Lastly, it inhibits PTP1B enzyme activity on the substrate pNPP with an IC50 value of 1600.0 nM after a 30-minute incubation, demonstrating considerable enzyme inhibitory potential..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Arachidic acid (Icosanoic Acid) is a saturated fatty acid found naturally in fish and vegetable oils (such as those from peanuts). It can also be formed by the hydrogenation of arachidonic acid. Diets rich in saturated fatty acids, such as arachidic acid, are known to increase serum low-density lipoproteins resulting in high blood cholesterol levels.
SynonymsIcosanoic Acid, eicosanoic acid
Chemical Properties
Molecular Weight312.53
FormulaC20H40O2
Cas No.506-30-9
SmilesCCCCCCCCCCCCCCCCCCCC(O)=O
Relative Density.0.884 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Chloroform: 50 mg/mL (159.98 mM), Sonication is recommended.
DMSO: 8.06 mg/mL (25.79 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.2 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/Chloroform
1mg5mg10mg50mg
1 mM3.1997 mL15.9985 mL31.9969 mL159.9846 mL
5 mM0.6399 mL3.1997 mL6.3994 mL31.9969 mL
10 mM0.3200 mL1.5998 mL3.1997 mL15.9985 mL
20 mM0.1600 mL0.7999 mL1.5998 mL7.9992 mL
Chloroform
1mg5mg10mg50mg
50 mM0.0640 mL0.3200 mL0.6399 mL3.1997 mL
100 mM0.0320 mL0.1600 mL0.3200 mL1.5998 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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