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NV03 is a selective antagonist of the UHRF1-H3K9me3 interaction (Kd=2.4 μM), binding to the UHRF1 tandem Tudor domain (TTD) to form a complex. It is suitable for cancer research. NV03 also functions as a ligand for E3 ligases in PROTAC synthesis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $165 | In Stock | |
5 mg | $413 | In Stock | |
10 mg | $689 | In Stock | |
25 mg | $1,360 | In Stock |
Description | NV03 is a selective antagonist of the UHRF1-H3K9me3 interaction (Kd=2.4 μM), binding to the UHRF1 tandem Tudor domain (TTD) to form a complex. It is suitable for cancer research. NV03 also functions as a ligand for E3 ligases in PROTAC synthesis. |
Targets&IC50 | UHRF1:2.4 μM (Kd) |
Synonyms | GIP (1-42)TFA, GIP (1-42), porcine TFA |
Molecular Weight | 389.52 |
Formula | C19H27N5O2S |
Cas No. | 2448341-58-8 |
Smiles | CCN(CC)CCCNC(=O)Cn1nc(C)n2c3ccsc3c(C)c2c1=O |
Relative Density. | 1.29 g/cm3 (Predicted) |
Color | White |
Appearance | Solid |
Storage | keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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