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1-beta-D-Arabinofuranosyluracil

🥰Excellent
Catalog No. T5979Cas No. 3083-77-0
Alias Uracil 1-β-D-arabinofuranoside

1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside), isolated from the Caribbean sponge [Tectitethya crypta], is a methoxyadenosine derivative with anti-inflammatory activity, analgesic, and vasodilation properties.

1-beta-D-Arabinofuranosyluracil

1-beta-D-Arabinofuranosyluracil

🥰Excellent
Purity: 99.77%
Catalog No. T5979Alias Uracil 1-β-D-arabinofuranosideCas No. 3083-77-0
1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside), isolated from the Caribbean sponge [Tectitethya crypta], is a methoxyadenosine derivative with anti-inflammatory activity, analgesic, and vasodilation properties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 mg$31In StockIn Stock
1 g$44In StockIn Stock
1 mL x 10 mM (in DMSO)$30In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.77%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside), isolated from the Caribbean sponge [Tectitethya crypta], is a methoxyadenosine derivative with anti-inflammatory activity, analgesic, and vasodilation properties.
In vivo
1-β-d-Arabinofuranosyluracil (ara-U) reduces a proliferation of L5178Y mouse lymphoma cells at 17 μm, concentration which, in a dose-response experiment, induced 50% inhibition of cell proliferation[1].
SynonymsUracil 1-β-D-arabinofuranoside
Chemical Properties
Molecular Weight244.2
FormulaC9H12N2O6
Cas No.3083-77-0
SmilesO[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C=C2
Relative Density.1.674g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (225.23 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.19 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0950 mL20.4750 mL40.9500 mL204.7502 mL
5 mM0.8190 mL4.0950 mL8.1900 mL40.9500 mL
10 mM0.4095 mL2.0475 mL4.0950 mL20.4750 mL
20 mM0.2048 mL1.0238 mL2.0475 mL10.2375 mL
50 mM0.0819 mL0.4095 mL0.8190 mL4.0950 mL
100 mM0.0410 mL0.2048 mL0.4095 mL2.0475 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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