Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 575.00 | |
5 mg | 35 days | $ 2,250.00 |
Description | Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization. |
Molecular Weight | 529.63 |
Formula | C31H35N3O5 |
CAS No. | 1020412-97-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 14 mg/mL
Ethanol: 1 mg/mL
DMSO: 20 mg/mL
DMSO:PBS (pH 7.2)(1:9): 0.1 mg/mL
You can also refer to dose conversion for different animals. More
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Tie2 Inhibitor 7 1020412-97-8 Tie-2 Inhibitor 7 inhibitor inhibit