Powder: -20°C for 3 years | In solvent: -80°C for 1 year
YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 2,420.00 | |
50 mg | 10-14 weeks | $ 3,180.00 | |
100 mg | 10-14 weeks | $ 4,300.00 |
Description | YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4. |
In vitro | Compared with Cl-amidine, YW3-56 shows >60-fold increase in cell growth inhibition efficacy (IC50 about 2.5 μM) but only 5-fold increase in PAD4 inhibition (IC sub>50 about 1-5 μM). At 2-4 μM concentrations, YW3-56 displays mainly cytostatic effects by slowing cell division, whereas at higher concentrations, it exerts cytotoxic effects by altering cell morphology and killing cells[1]. |
Synonyms | YW3-56 |
Molecular Weight | 494.03 |
Formula | C27H32ClN5O2 |
CAS No. | 1374311-17-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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YW3-56 1374311-17-7 YW3 56 YW-3-56 YW356 inhibitor inhibit