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Ocaratuzumab
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Catalog No. T76821Cas No. 1169956-08-4
Alias LY2469298, LY 2469298, Humanized Anti-MS4A1 Recombinant Antibody, AME133v, AME 133v
Ocaratuzumab (AME-133v) is an Fc-engineered antibody and humanized monoclonal antibody targeting CD20 (Kd≈100 pM), exhibiting antibody-dependent cellular cytotoxicity (ADCC) in chronic lymphocytic leukemia.
Ocaratuzumab
Ocaratuzumab
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Purity: 95%
Catalog No. T76821Alias LY2469298, LY 2469298, Humanized Anti-MS4A1 Recombinant Antibody, AME133v, AME 133vCas No. 1169956-08-4
Ocaratuzumab (AME-133v) is an Fc-engineered antibody and humanized monoclonal antibody targeting CD20 (Kd≈100 pM), exhibiting antibody-dependent cellular cytotoxicity (ADCC) in chronic lymphocytic leukemia.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $290 | - | In Stock | |
| 5 mg | $755 | - | In Stock | |
| 10 mg | $1,200 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.2% (SDS-PAGE); 98.0% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Ocaratuzumab (AME-133v) is an Fc-engineered antibody and humanized monoclonal antibody targeting CD20 (Kd≈100 pM), exhibiting antibody-dependent cellular cytotoxicity (ADCC) in chronic lymphocytic leukemia. |
| In vitro | Ocaratuzumab (0.027-20 μg/mL) can concentration-dependently inhibit the binding of biotinylated Rituximab to CD20 on the surface of SKW6.4 cells [1]. |
| Synonyms | LY2469298, LY 2469298, Humanized Anti-MS4A1 Recombinant Antibody, AME133v, AME 133v |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD20 |
| Molecular Weight | 145.27 kDa |
| Cas No. | 1169956-08-4 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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