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Ocaratuzumab

(Synonyms: LY2469298, LY 2469298, Humanized Anti-MS4A1 Recombinant Antibody, AME133v, AME 133v) Copy Product Info
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Synonyms: LY2469298, LY 2469298, Humanized Anti-MS4A1 Recombinant Antibody, AME133v, AME 133v

Catalog No. T76821 Copy Product Info
Purity: 95%
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Ocaratuzumab (AME-133v) is an Fc-engineered antibody and humanized monoclonal antibody targeting CD20 (Kd≈100 pM), exhibiting antibody-dependent cellular cytotoxicity (ADCC) in chronic lymphocytic leukemia.
Ocaratuzumab
Cas No. 1169956-08-4
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$290-In Stock
5 mg$755-In Stock
10 mg$1,200-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.2% (SDS-PAGE); 98.0% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Ocaratuzumab (AME-133v) is an Fc-engineered antibody and humanized monoclonal antibody targeting CD20 (Kd≈100 pM), exhibiting antibody-dependent cellular cytotoxicity (ADCC) in chronic lymphocytic leukemia.
In vitro
Ocaratuzumab (0.027-20 μg/mL) can concentration-dependently inhibit the binding of biotinylated Rituximab to CD20 on the surface of SKW6.4 cells [1].
SynonymsLY2469298, LY 2469298, Humanized Anti-MS4A1 Recombinant Antibody, AME133v, AME 133v
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCD20
Chemical Properties
Molecular Weight145.27 kDa
Cas No.1169956-08-4
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Related Tags: Ocaratuzumab chemical structure | Ocaratuzumab in vitro | Ocaratuzumab molecular weight