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Anti-TIM-1/KIM-1/HAVCR1 Antibody (2A859) is an antibody targeting TIM-1/KIM-1/HAVCR1. Anti-TIM-1/KIM-1/HAVCR1 Antibody (2A859) can be used in ELISA,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-TIM-1/KIM-1/HAVCR1 Antibody (2A859) is an antibody targeting TIM-1/KIM-1/HAVCR1. Anti-TIM-1/KIM-1/HAVCR1 Antibody (2A859) can be used in ELISA,WB. |
| Synonyms | TIMD-1, TIMD1, TIM-1, TIM1, TIM, KIM-1, KIM1, HAVCR-1, HAVCR1, HAVCR, CD365 |
| Ig Type | Rabbit IgG |
| Clone | 2A859 |
| Reactivity | Human, Mouse |
| Verified Activity | 1. Western Blot -Positive WB detected in: RAW264.7 whole cell lysate(20µg), 293T whole cell lysate(20µg), JK whole cell lysate(20µg), MCF7 whole cell lysate(20µg) -All lanes: HAVCR1 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 40 kDa -Observed band size: 50 kDa -Exposure time: 120s 2. IHC image of TMAH-00530 diluted at 1:50 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody |
| Application | |
| Recommended Dose | WB:1:500-1:5000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair. (Microbial infection) Acts as a receptor for Hepatitis A virus. (Microbial infection) Acts as a receptor for Ebolavirus and Marburg virus by binding exposed phosphatidyl-serine at the surface of virion membrane. Serves as a dual receptor for Ebolavirus by also interacting with envelope glycoprotein GP. (Microbial infection) Acts as a receptor for Dengue virus by binding exposed phosphatidyl-serine at the surface of virion membrane. (Microbial infection) Acts as a receptor for Zika virus by binding to envelope protein E. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human TIM 1 |
| Antigen Species | Human |
| Gene Name | HAVCR1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology, Microbiology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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