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Gitoxin

Name: Gitoxin
Brand: TargetMol
SKU: TN4134
Price: 91 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN4134Cas No. 4562-36-1

Gitoxin is a natural Na⁺/K⁺-ATPase inhibitor and metabolite of digitoxin, exhibiting antiarrhythmic activity with μM-level inhibition of human erythrocyte isoenzymes.

Gitoxin

🥰Excellent

Catalog No. TN4134Cas No. 4562-36-1

Gitoxin is a natural Na⁺/K⁺-ATPase inhibitor and metabolite of digitoxin, exhibiting antiarrhythmic activity with μM-level inhibition of human erythrocyte isoenzymes.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$91	-	In Stock
2 mg	$137	-	In Stock
5 mg	$228	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description

Gitoxin is a natural Na⁺/K⁺-ATPase inhibitor and metabolite of digitoxin, exhibiting antiarrhythmic activity with μM-level inhibition of human erythrocyte isoenzymes.

Chemical Properties

Molecular Weight	780.94
Formula	C₄₁H₆₄O₁₄
Cas No.	4562-36-1
Smiles	O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5C[C@H](O)[C@H](O[C@H]6C[C@H](O)[C@H](O[C@H]7C[C@H](O)[C@H](O)[C@@H](C)O7)[C@@H](C)O6)[C@@H](C)O5)CC4)[H])(CC[C@]1(C)[C@H]([C@@H](O)C2)C8=CC(=O)OC8)[H])[H]
Relative Density.	1.36g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 6 mg/mL (7.68 mM), Sonication and heating are recommended.

Solution Preparation Table

Ethanol

	1mg	5mg	10mg	50mg
1 mM	1.2805 mL	6.4025 mL	12.8051 mL	64.0254 mL
5 mM	0.2561 mL	1.2805 mL	2.5610 mL	12.8051 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc