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Uliledlimab
😃Good
Catalog No. T76730Cas No. 2378407-27-1
Alias TJ-004309, TJ004309
Uliledlimab is a humanized monoclonal antibody with potent inhibitory activity against CD73, the ecto-5'-nucleotidase enzyme that catalyzes the conversion of extracellular AMP to adenosine. Uliledlimab reduces extracellular adenosine production, thereby modulating immunosuppressive pathways. Uliledlimab holds significant potential for use in immuno-oncology and cancer research.
Uliledlimab
Uliledlimab
😃Good
Purity: 95%
Catalog No. T76730Alias TJ-004309, TJ004309Cas No. 2378407-27-1
Uliledlimab is a humanized monoclonal antibody with potent inhibitory activity against CD73, the ecto-5'-nucleotidase enzyme that catalyzes the conversion of extracellular AMP to adenosine. Uliledlimab reduces extracellular adenosine production, thereby modulating immunosuppressive pathways. Uliledlimab holds significant potential for use in immuno-oncology and cancer research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $339 | - | In Stock | |
| 5 mg | $730 | - | In Stock | |
| 10 mg | $1,160 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:95.5% (SDS-PAGE); 95.1% (SEC-HPLC)
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| Description | Uliledlimab is a humanized monoclonal antibody with potent inhibitory activity against CD73, the ecto-5'-nucleotidase enzyme that catalyzes the conversion of extracellular AMP to adenosine. Uliledlimab reduces extracellular adenosine production, thereby modulating immunosuppressive pathways. Uliledlimab holds significant potential for use in immuno-oncology and cancer research. |
| In vitro | Uliledlimab completely inhibits the enzymatic activity of CD73 by binding to the C-terminal domain of the CD73 protein broussonetia papyrifera. By blocking adenosine production, Uliledlimab alleviates immune cell suppression, enhances the activity of CD8+ T cells and macrophages, and ultimately strengthens the anti-tumor immune response [1]. |
| In vivo | Uliledlimab, when used alone or in combination with the PD-L1 inhibitor Atezolizumab, can effectively inhibit the growth of solid tumors [1]. |
| Synonyms | TJ-004309, TJ004309 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | NT5E/CD73 |
| Molecular Weight | 145.02 kDa |
| Cas No. | 2378407-27-1 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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