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Anti-CD40 Antibody (9S211)
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Catalog No. TMAY-01155
Alias TRAP, Tnfrsf5, T-BAM, p50, IMD3, Igm, HIGM1, gp39, CD40 molecule, TNF receptor superfamily member 5, Bp50, AI326936
Anti-CD40 Antibody (9S211) is a Mouse antibody targeting CD40. Anti-CD40 Antibody (9S211) can be used in FCM.
Anti-CD40 Antibody (9S211)
Anti-CD40 Antibody (9S211)
😃Good
Catalog No. TMAY-01155Alias TRAP, Tnfrsf5, T-BAM, p50, IMD3, Igm, HIGM1, gp39, CD40 molecule, TNF receptor superfamily member 5, Bp50, AI326936
Anti-CD40 Antibody (9S211) is a Mouse antibody targeting CD40. Anti-CD40 Antibody (9S211) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $292 | 7-10 days |
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Chemical Properties
| Description | Anti-CD40 Antibody (9S211) is a Mouse antibody targeting CD40. Anti-CD40 Antibody (9S211) can be used in FCM. |
| Alias | TRAP, Tnfrsf5, T-BAM, p50, IMD3, Igm, HIGM1, gp39, CD40 molecule, TNF receptor superfamily member 5, Bp50, AI326936 |
| Ig Type | Monoclonal Mouse IgG2b |
| Clone | 9S211 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of human CD40 expression on human whole blood lymphocytes. Human whole blood lymphocytes were stained with purified anti-Human CD40, then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD40 / TNFRSF5 (rh CD40 / TNFRSF5; TMPY-01181; NP_001241.1; Met1-Arg193). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human CD40 / TNFRSF5 protein (TMPY-01181) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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