Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glycolate oxidase-IN-1 (compound 26), a salicylic acid derivative, serves as an inhibitor of glycolate oxidase (GO) and exhibits an inhibitory concentration (IC50) of 38.2 μM. It is efficacious in reducing oxalate production in hyperoxaluric hepatocytes and has potential applications in researching primary hyperoxaluria type 1 (PH1) [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | Glycolate oxidase-IN-1 (compound 26), a salicylic acid derivative, serves as an inhibitor of glycolate oxidase (GO) and exhibits an inhibitory concentration (IC50) of 38.2 μM. It is efficacious in reducing oxalate production in hyperoxaluric hepatocytes and has potential applications in researching primary hyperoxaluria type 1 (PH1) [1]. |
In vitro | When treated with Glycolate oxidase-IN-1 (compound 26) (0-12.5 μM, 48 h), murine hepatocytes exhibited a significant reduction in excreted oxalate levels, with a 67.3 ± 32% decrease observed at a concentration of 6.25 μM. |
Molecular Weight | 232.19 |
Formula | C12H8O5 |
CAS No. | 330977-65-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Glycolate oxidase-IN-1 330977-65-6 inhibitor inhibit