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γ-Glutamyl-S-allylcysteine

Name: γ-Glutamyl-S-allylcysteine
Brand: TargetMol
SKU: T41054
Price: 88 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T41054Cas No. 91216-95-4

Alias L-γ-Glutamyl-(S)-Allyl-Cysteine

γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a γ-glutamyl peptide derived from Allium sativum L., known for its anti-glycation and antioxidant properties, as well as its ability to inhibit cholesterol biosynthesis.

γ-Glutamyl-S-allylcysteine

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Purity: 98.84%

Catalog No. T41054Alias L-γ-Glutamyl-(S)-Allyl-CysteineCas No. 91216-95-4

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$88	In Stock	In Stock
5 mg	$213	In Stock	In Stock
10 mg	$322	In Stock	In Stock
25 mg	$517	In Stock	In Stock
50 mg	$728	In Stock	In Stock
100 mg	$982	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98.84%

Appearance:Solid

Color:White

Resource Download

COA HPLC MS HNMR

Product Introduction

Bioactivity

Description	γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a γ-glutamyl peptide derived from Allium sativum L., known for its anti-glycation and antioxidant properties, as well as its ability to inhibit cholesterol biosynthesis.
In vitro	In a concentration-dependent manner, γ-Glutamyl-S-allylcysteine (0.1-2.5 mg/mL) inhibits the increase in fluorescence intensity at around 440 nm and reduces the free lysine side-chain reaction [2].At a concentration of 2.5 mg/mL, γ-Glutamyl-S-allylcysteine prevents the specific decrease in glycation of BSA α-helical content and the increase in β-fold in vitro [1].At a concentration of 2.5 mg/mL, γ-Glutamyl-S-allylcysteine inhibits the formation of protein cross-linking polymers [2].γ-Glutamyl-S-allylcysteine (10, 40, 160 μg/mL) possesses the ability to scavenge free radicals and chelate metals [2].
Synonyms	L-γ-Glutamyl-(S)-Allyl-Cysteine

Chemical Properties

Molecular Weight	290.34
Formula	C₁₁H₁₈N₂O₅S
Cas No.	91216-95-4
Smiles	N[C@@H](CCC(=O)N[C@@H](CSCC=C)C(O)=O)C(O)=O
Relative Density.	1.327 g/cm3 (Predicted)
Sequence	gGlu-Cys(allyl)(allyl)
Sequence Short	XX

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 65 mg/mL (223.88 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	3.4442 mL	17.2212 mL	34.4424 mL	172.2119 mL
5 mM	0.6888 mL	3.4442 mL	6.8885 mL	34.4424 mL
10 mM	0.3444 mL	1.7221 mL	3.4442 mL	17.2212 mL
20 mM	0.1722 mL	0.8611 mL	1.7221 mL	8.6106 mL
50 mM	0.0689 mL	0.3444 mL	0.6888 mL	3.4442 mL
100 mM	0.0344 mL	0.1722 mL	0.3444 mL	1.7221 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc