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Anti-TIM-1/KIM-1/HAVCR1 Antibody (7M781) is a Mouse antibody targeting TIM-1/KIM-1/HAVCR1. Anti-TIM-1/KIM-1/HAVCR1 Antibody (7M781) can be used in ELISA.
Description | Anti-TIM-1/KIM-1/HAVCR1 Antibody (7M781) is a Mouse antibody targeting TIM-1/KIM-1/HAVCR1. Anti-TIM-1/KIM-1/HAVCR1 Antibody (7M781) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 7M781 |
Reactivity | Rhesus |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rhesus KIM-1 / TIM1 / HACVR1 (TMPY-01671; BAJ61041.1; Asp20-Val135). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest levels in the kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy, and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling. |
Conjucates | Unconjugated |
Immunogen | Recombinant Rhesus KIM-1 / TIM1 / HACVR1 Protein (TMPY-01671) |
Antigen Species | Rhesus |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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