Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-TGF beta 1 Antibody (6O746)

😃Good
Catalog No. TMAY-01178
Alias transforming growth factor, β1, transforming growth factor, beta 1, TGF β1

Anti-TGF beta 1 Antibody (6O746) is a Rabbit antibody targeting TGF beta 1. Anti-TGF beta 1 Antibody (6O746) can be used in ELISA.

Anti-TGF beta 1 Antibody (6O746)

Anti-TGF beta 1 Antibody (6O746)

😃Good
Catalog No. TMAY-01178Alias transforming growth factor, β1, transforming growth factor, beta 1, TGF β1
Anti-TGF beta 1 Antibody (6O746) is a Rabbit antibody targeting TGF beta 1. Anti-TGF beta 1 Antibody (6O746) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
20 μL$92 7-10 days
100 μL$269 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-TGF beta 1 Antibody (6O746) is a Rabbit antibody targeting TGF beta 1. Anti-TGF beta 1 Antibody (6O746) can be used in ELISA.
Aliastransforming growth factor, β1, transforming growth factor, beta 1, TGF β1
Ig Type
Monoclonal Rabbit IgG
Clone
6O746
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human TGF-beta 1 (rh TGF-beta 1; TMPY-01133; NP_000651.3; Met 1-Ser 390).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, differentiation, motility, adhesion and death. TGF-beta 1 positively and negatively regulates many other growth factors. It inhibits the secretion and activity of many other cytokines including interferon-γ, tumor necrosis factor-alpha and various interleukins. It can also decrease the expression levels of cytokine receptors. Meanwhile, TGF-beta 1 also increases the expression of certain cytokines in T cells and promotes their proliferation, particularly if the cells are immature. TGF-beta 1 also inhibits proliferation and stimulates apoptosis of B cells, and plays a role in controlling the expression of antibody, transferrin and MHC class II proteins on immature and mature B cells. As for myeloid cells, TGF-beta 1can inhibit their proliferation and prevent their production of reactive oxygen and nitrogen intermediates. However, as with other cell types, TGF-beta 1 also has the opposite effect on cells of myeloid origin. TGF-beta 1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Once cells lose their sensitivity to TGF-beta1-mediated growth inhibition, autocrine TGF-beta signaling can promote tumorigenesis. Elevated levels of TGF-beta1 are often observed in advanced carcinomas, and have been correlated with increased tumor invasiveness and disease progression.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
HRP
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Human TGF-beta1 protein (TMPY-01133)
Antigen Species
Human
Biology Area
Early Mesodermal Lineage Markers, Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-TGF beta 1 Antibody (6O746) | purchase Anti-TGF beta 1 Antibody (6O746) | Anti-TGF beta 1 Antibody (6O746) cost | order Anti-TGF beta 1 Antibody (6O746)