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Fumonisin B1

Name: Fumonisin B1
Brand: TargetMol
SKU: T15356
Rating: 4.5 (1 reviews)

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Catalog No. T15356Cas No. 116355-83-0

Alias Fumonisin-B1

Fumonisin B1 (Fumonisin-B1) is a mycotoxin produced by Fusarium oxysporum that is widely present in crops, contaminating them and posing a significant food safety hazard.Fumonisin B1 is structurally a sphingosine and sphingomyelin analog, and inhibits the biosynthesis of complex sphingolipids through the inhibition of ceramidic synthases.

Fumonisin B1

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Catalog No. T15356Alias Fumonisin-B1Cas No. 116355-83-0

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$292	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Fumonisin B1 (Fumonisin-B1) is a mycotoxin produced by Fusarium oxysporum that is widely present in crops, contaminating them and posing a significant food safety hazard.Fumonisin B1 is structurally a sphingosine and sphingomyelin analog, and inhibits the biosynthesis of complex sphingolipids through the inhibition of ceramidic synthases.
In vitro	The mRNA expression of P21 was significantly increased after 0.1 μmol/L Fumonisin B1 treatment, and the mRNA expression of P21 was significantly decreased after 10.0 and 100.0 μmol / l Fumonisin B1 treatment[1].
Synonyms	Fumonisin-B1

Chemical Properties

Molecular Weight	721.83
Formula	C₃₄H₅₉NO₁₅
Cas No.	116355-83-0
Smiles	O.CCCC[C@@H](C)[C@@H](OC(=O)C[C@@H](CC(O)=O)C(O)=O)C(C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)OC(=O)C[C@@H](CC(O)=O)C(O)=O
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 16 mg/mL (22.17 mM), Sonication is recommended.

Methanol: 5 mg/mL (6.93 mM), Sonication is recommended.

Solution Preparation Table

Methanol/H2O

	1mg	5mg	10mg	50mg
1 mM	1.3854 mL	6.9268 mL	13.8537 mL	69.2684 mL
5 mM	0.2771 mL	1.3854 mL	2.7707 mL	13.8537 mL

H2O

	1mg	5mg	10mg	50mg
10 mM	0.1385 mL	0.6927 mL	1.3854 mL	6.9268 mL
20 mM	0.0693 mL	0.3463 mL	0.6927 mL	3.4634 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc