Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-VCAM-1 Antibody (8X486)
😃Good
Catalog No. TMAY-03152
Alias VCAM-1, vascular cell adhesion molecule 1, INCAM-100, CD106
Anti-VCAM-1 Antibody (8X486) is a Rabbit antibody targeting VCAM-1. Anti-VCAM-1 Antibody (8X486) can be used in ELISA.
Anti-VCAM-1 Antibody (8X486)
Anti-VCAM-1 Antibody (8X486)
😃Good
Catalog No. TMAY-03152Alias VCAM-1, vascular cell adhesion molecule 1, INCAM-100, CD106
Anti-VCAM-1 Antibody (8X486) is a Rabbit antibody targeting VCAM-1. Anti-VCAM-1 Antibody (8X486) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-VCAM-1 Antibody (8X486) is a Rabbit antibody targeting VCAM-1. Anti-VCAM-1 Antibody (8X486) can be used in ELISA. |
| Synonyms | VCAM-1, vascular cell adhesion molecule 1, INCAM-100, CD106 |
| Ig Type | Rabbit IgG |
| Clone | 8X486 |
| Reactivity | Mouse |
| Specificity | Mouse VCAM-1/CD106 No cross-reactivity in ELISA with Human VCAM1 Human ICAM1 Human ICAM2 Human ICAM3 Human SELL Human SELP |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse VCAM-1 / CD106 (rM VCAM-1 / CD106; TMPY-01830; NP_035823.3; Met1-Glu698). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains are generated by alternative splicing, with the longer form predominant. VCAM-1 is an endothelial ligand for very late antigen-4 (VLA-4) and α4ß7 integrin expressed on leukocytes, and thus mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 expression is induced on endothelial cells during inflammatory bowel disease, atherosclerosis, allograft rejection, infection, and asthmatic responses. During these responses, VCAM-1 forms a scaffold for leukocyte migration. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. VCAM-1 has been identified as a potential anti-inflammatory therapeutic target, the hypothesis being that reduced expression of VCAM-1 will slow the development of atherosclerosis. In addition, VCAM-1-activated signals in endothelial cells are regulated by cytokines indicating that it is important to consider both endothelial cell adhesion molecule expression and function during inflammatory processes.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse VCAM-1 / CD106 protein (TMPY-01830) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-VCAM-1 Antibody (8X486) | purchase Anti-VCAM-1 Antibody (8X486) | Anti-VCAM-1 Antibody (8X486) cost | order Anti-VCAM-1 Antibody (8X486)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.