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Manghaslin

Name: Manghaslin
Brand: TargetMol
SKU: TN2130
Price: 113 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN2130Cas No. 55696-57-6

Alias Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside

Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also shows inhibitory activity against AChE

Manghaslin

🥰Excellent

Purity: 99.98%

Catalog No. TN2130Alias Quercetin 3-O-rutinoside-(1->2)-O-rhamnosideCas No. 55696-57-6

Pack Size	Price	Availability
1 mg	$113	In Stock
5 mg	$222	In Stock
10 mg	$328	In Stock
25 mg	$552	In Stock
1 mL x 10 mM (in DMSO)	$319	In Stock

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Batch Information

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Purity:99.98%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also shows inhibitory activity against AChE
In vitro	Global Natural Products Social (GNPS) Molecular Networking was applied to trace the phenolic compounds in plants, which allowed the characterization of 9 procyanidins and 11 flavonoid glycosides (di-, tri-, or tetra-saccharides of kaempferol, quercetin, isorhamnetin and myricetin) in litchi pulp extracts.
Synonyms	Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside

Chemical Properties

Molecular Weight	756.66
Formula	C₃₃H₄₀O₂₀
Cas No.	55696-57-6
Smiles	O(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC(O)=C(O)C=C3)[C@H]4[C@H](O[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@@H](CO[C@H]6[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O6)O4
Relative Density.	1.79 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (72.69 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (1.32 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3216 mL	6.6080 mL	13.2160 mL	66.0799 mL
5 mM	0.2643 mL	1.3216 mL	2.6432 mL	13.2160 mL
10 mM	0.1322 mL	0.6608 mL	1.3216 mL	6.6080 mL
20 mM	0.0661 mL	0.3304 mL	0.6608 mL	3.3040 mL
50 mM	0.0264 mL	0.1322 mL	0.2643 mL	1.3216 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc