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Synonyms: Splicing factor 3B subunit 1, Spliceosome-associated protein 155, SF3b155, SAP155, SAP 155, Pre-mRNA-splicing factor SF3b 155 kDa subunit
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-SF3B1 Antibody (2V152) is an antibody targeting SF3B1. Anti-SF3B1 Antibody (2V152) can be used in ELISA,IF,IHC,WB. |
| Synonyms | Splicing factor 3B subunit 1, Spliceosome-associated protein 155, SF3b155, SAP155, SAP 155, Pre-mRNA-splicing factor SF3b 155 kDa subunit |
| Ig Type | Rabbit IgG |
| Clone | 2V152 |
| Reactivity | Human, Mouse |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200; IF:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. Nucleus speckle. Note=During mitosis, transiently dispersed from the nuclear speckles to the cytoplasm. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. Together with other U2 snRNP complex components may also play a role in the selective processing of microRNAs (miRNAs) from the long primary miRNA transcript, pri-miR-17-92. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human SF3B1 |
| Antigen Species | Human |
| Gene Name | SF3B1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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