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N-(4-Carboxycyclohexylmethyl)maleimide

🥰Excellent
Catalog No. T16167Cas No. 64987-82-2

N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-like PROTAC linker that can be used to synthesize PROTAC molecules.

N-(4-Carboxycyclohexylmethyl)maleimide

N-(4-Carboxycyclohexylmethyl)maleimide

🥰Excellent
Purity: 98.04%
Catalog No. T16167Cas No. 64987-82-2
N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-like PROTAC linker that can be used to synthesize PROTAC molecules.
Pack SizePriceAvailabilityQuantity
25 mg$105In Stock
50 mg$157In Stock
100 mg$235In Stock
500 mg$517In Stock
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Batch Information

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Purity:98.04%
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Product Introduction

Bioactivity
Description
N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-like PROTAC linker that can be used to synthesize PROTAC molecules.
Chemical Properties
Molecular Weight237.25
FormulaC12H15NO4
Cas No.64987-82-2
SmilesO=C1C=CC(=O)N1CC2CCC(C(=O)O)CC2
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 180 mg/mL (758.69 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.2150 mL21.0748 mL42.1496 mL210.7482 mL
5 mM0.8430 mL4.2150 mL8.4299 mL42.1496 mL
10 mM0.4215 mL2.1075 mL4.2150 mL21.0748 mL
20 mM0.2107 mL1.0537 mL2.1075 mL10.5374 mL
50 mM0.0843 mL0.4215 mL0.8430 mL4.2150 mL
100 mM0.0421 mL0.2107 mL0.4215 mL2.1075 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

N-(4-Carboxycyclohexylmethyl)maleimideN(4Carboxycyclohexylmethyl)maleimideN (4 Carboxycyclohexylmethyl)maleimideAlkyl-Chain
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