keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HXR9 hydrochloride, a cell-permeable peptide and competitive antagonist of the HOX/PBX interaction, selectively reduces cell proliferation and induces apoptosis in cells with elevated HOXA/PBX3 gene expression, notably MLL-rearranged leukemic cells [1] [2] [3]. By inhibiting the interaction between HOX proteins and the transcription factor PBX, which associates with HOX proteins in paralogue groups 1 to 8, it disrupts a critical regulatory mechanism in these cells.
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Description | HXR9 hydrochloride, a cell-permeable peptide and competitive antagonist of the HOX/PBX interaction, selectively reduces cell proliferation and induces apoptosis in cells with elevated HOXA/PBX3 gene expression, notably MLL-rearranged leukemic cells [1] [2] [3]. By inhibiting the interaction between HOX proteins and the transcription factor PBX, which associates with HOX proteins in paralogue groups 1 to 8, it disrupts a critical regulatory mechanism in these cells. |
Molecular Weight | 2754.67 |
Formula | C119H194ClN53O20S |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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HXR9 hydrochloride inhibitor inhibit