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Sasanlimab
(Synonyms: PF-06801591) Copy Product Info
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Synonyms: PF-06801591
Catalog No. T80611 Copy Product Info
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Sasanlimab represents a highly specialized humanized IgG4 monoclonal antibody specifically engineered to target the human programmed cell death protein 1 (PD-1) with exceptional binding affinity. It effectively facilitates the measurable blockade of the PD-1/PD-L1 and PD-1/PD-L2 inhibitory axes across various preclinical experimental models to evaluate the restoration of T-cell mediated anti-tumor immunity and the reversal of immune exhaustion during strictly monitored laboratory observation periods.
Sasanlimab
Cas No. 2206792-50-7
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $377 | 4-6 weeks | 4-6 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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Storage & Solubility Information
| Description | Sasanlimab represents a highly specialized humanized IgG4 monoclonal antibody specifically engineered to target the human programmed cell death protein 1 (PD-1) with exceptional binding affinity. It effectively facilitates the measurable blockade of the PD-1/PD-L1 and PD-1/PD-L2 inhibitory axes across various preclinical experimental models to evaluate the restoration of T-cell mediated anti-tumor immunity and the reversal of immune exhaustion during strictly monitored laboratory observation periods. |
| Targets & IC50 | PD-1:< 2 nM, PD-1/PD-L1:~1.0 nM(Kd) |
| Synonyms | PF-06801591 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | PD-1 |
| Cas No. | 2206792-50-7 |
| Isotype | IgG4 (S228P) |
| Recommended Isotype Control |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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