keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Influenza A virus-IN-8 (S5), a macrocyclic peptide, exhibits no cytotoxicity and functions as a potent inhibitor of Influenza A Virus (IAV), demonstrating significant protease stability. It has IC50 values of 6.7 nM for H1 and 6.6 nM for H5 variants, indicating strong inhibitory effects. Furthermore, it has a high affinity for H1 variants, binding to a conserved region in the HA stem with a dissociation constant (Kd) of 1.0 nM [1].
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Description | Influenza A virus-IN-8 (S5), a macrocyclic peptide, exhibits no cytotoxicity and functions as a potent inhibitor of Influenza A Virus (IAV), demonstrating significant protease stability. It has IC50 values of 6.7 nM for H1 and 6.6 nM for H5 variants, indicating strong inhibitory effects. Furthermore, it has a high affinity for H1 variants, binding to a conserved region in the HA stem with a dissociation constant (Kd) of 1.0 nM [1]. |
Molecular Weight | 2200.48 |
Formula | C104H142N28O24S |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Influenza A virus-IN-8 inhibitor inhibit