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Dual FAAH/sEH-IN-1

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Catalog No. T63536Cas No. 2756099-59-7

Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.

Dual FAAH/sEH-IN-1

Dual FAAH/sEH-IN-1

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Purity: 99.89%
Catalog No. T63536Cas No. 2756099-59-7
Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$100In StockIn Stock
5 mg$243In StockIn Stock
10 mg$323In StockIn Stock
25 mg$491In StockIn Stock
50 mg$659In StockIn Stock
100 mg$882In StockIn Stock
200 mg$1,170-In Stock
1 mL x 10 mM (in DMSO)$300In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.89%
Appearance:Solid
Color:White
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Product Introduction

Dual FAAH/sEH-IN-1 AI Summary
Dual FAAH/sEH-IN-1 exhibits bioactivities as an inhibitor of human FAAH with an IC50 of 7.0 nM and as an inhibitor of human sEH with an IC50 of 9.6 nM..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.
Chemical Properties
Molecular Weight512.04
FormulaC25H22ClN3O3S2
Cas No.2756099-59-7
SmilesN(C(=O)C1CCN(S(=O)(=O)C2=C(Cl)C=CC=C2)CC1)C3=CC=C(C4=NC=5C(S4)=CC=CC5)C=C3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (87.88 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9530 mL9.7649 mL19.5297 mL97.6486 mL
5 mM0.3906 mL1.9530 mL3.9059 mL19.5297 mL
10 mM0.1953 mL0.9765 mL1.9530 mL9.7649 mL
20 mM0.0976 mL0.4882 mL0.9765 mL4.8824 mL
50 mM0.0391 mL0.1953 mL0.3906 mL1.9530 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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