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Sodium taurocholate

🥰Excellent
Catalog No. TWA2417Cas No. 145-42-6
Alias Taurocholate Sodium

Sodium taurocholate is a biologically active compound that can inhibit bile duct injury induced by hepatic artery ligation by upregulating VEGF-A expression. It also exhibits immunomodulatory effects and can be used to induce pancreatitis models.

Sodium taurocholate

Sodium taurocholate

🥰Excellent
Purity: 99.64%
Catalog No. TWA2417Alias Taurocholate SodiumCas No. 145-42-6
Sodium taurocholate is a biologically active compound that can inhibit bile duct injury induced by hepatic artery ligation by upregulating VEGF-A expression. It also exhibits immunomodulatory effects and can be used to induce pancreatitis models.
Pack SizePriceAvailabilityQuantity
500 mg$50In Stock
1 g$64In Stock
5 g$105In Stock
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Purity:99.64%
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Product Introduction

Bioactivity
Description
Sodium taurocholate is a biologically active compound that can inhibit bile duct injury induced by hepatic artery ligation by upregulating VEGF-A expression. It also exhibits immunomodulatory effects and can be used to induce pancreatitis models.
AliasTaurocholate Sodium
Chemical Properties
Molecular Weight537.69
FormulaC26H44NO7S.Na
Cas No.145-42-6
Smiles[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
Relative Density.1.177 g/cm3 at 22.5℃
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 53.76 mg/mL (99.98 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.8598 mL9.2990 mL18.5981 mL92.9904 mL
5 mM0.3720 mL1.8598 mL3.7196 mL18.5981 mL
10 mM0.1860 mL0.9299 mL1.8598 mL9.2990 mL
20 mM0.0930 mL0.4650 mL0.9299 mL4.6495 mL
50 mM0.0372 mL0.1860 mL0.3720 mL1.8598 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

VEGFRVEGF-A expressionVascular endothelial growth factor receptorTumor necrosis factor-αTaurocholic acidSodium taurocholate hydrateSodium taurocholateN-CholoyltaurineInhibitorinhibitImmunoregulationI nterleukin-1βhepatic arteryEndogenous MetaboliteCD4+/CD8+
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