Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antitumor agent-61 (Compound 9b), an Irinotecan (Ir) derivative, demonstrates potent anticancer activity, as evidenced by its IC50 values ranging from 0.92 to 3.23 μM against six human cancer cell lines: SK-OV-3, SK-OV-3/CDDP, U2OS, MCF-7, A549, and MG-63. It specifically induces apoptosis in SK-OV-3 cells via mitochondrial pathways [1].
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Description | Antitumor agent-61 (Compound 9b), an Irinotecan (Ir) derivative, demonstrates potent anticancer activity, as evidenced by its IC50 values ranging from 0.92 to 3.23 μM against six human cancer cell lines: SK-OV-3, SK-OV-3/CDDP, U2OS, MCF-7, A549, and MG-63. It specifically induces apoptosis in SK-OV-3 cells via mitochondrial pathways [1]. |
Molecular Weight | 992.08 |
Formula | C54H63FN5O10P |
CAS No. | 2408917-12-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Antitumor agent-61 2408917-12-2 inhibitor inhibit