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Notoginsenoside R2

🥰Excellent
Catalog No. T6S1587Cas No. 80418-25-3
Alias Ginsenoside Ng-R2, 20(S)-Notoginsenoside R2

Notoginsenoside R2 (20(S)-Notoginsenoside R2) has neuroprotection against 6-OHDA-induced neurotoxicity, is associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathways.

Notoginsenoside R2
Other Forms of Notoginsenoside R2:
20(R)-Notoginsenoside R2TN1101948046-15-9
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Notoginsenoside R2

🥰Excellent
Purity: 99.83%
Catalog No. T6S1587Alias Ginsenoside Ng-R2, 20(S)-Notoginsenoside R2Cas No. 80418-25-3
Notoginsenoside R2 (20(S)-Notoginsenoside R2) has neuroprotection against 6-OHDA-induced neurotoxicity, is associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathways.
Pack SizePriceAvailabilityQuantity
1 mg$33In Stock
5 mg$70In Stock
10 mg$100In Stock
25 mg$163In Stock
50 mg$239In Stock
100 mg$356In Stock
1 mL x 10 mM (in DMSO)$120In Stock
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Purity:99.83%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Notoginsenoside R2 (20(S)-Notoginsenoside R2) has neuroprotection against 6-OHDA-induced neurotoxicity, is associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathways.
SynonymsGinsenoside Ng-R2, 20(S)-Notoginsenoside R2
Chemical Properties
Molecular Weight770.99
FormulaC41H70O13
Cas No.80418-25-3
Smiles[H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])[C@H](C[C@@]21C)O[C@]1([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@]1([H])OC[C@@H](O)[C@H](O)[C@H]1O)[C@@](C)(O)CCC=C(C)C
Relative Density.1.314g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 25 mg/mL (32.43 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2970 mL6.4852 mL12.9703 mL64.8517 mL
5 mM0.2594 mL1.2970 mL2.5941 mL12.9703 mL
10 mM0.1297 mL0.6485 mL1.2970 mL6.4852 mL
20 mM0.0649 mL0.3243 mL0.6485 mL3.2426 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

P90RSKNrf2Notoginsenoside R-2Notoginsenoside R2Notoginsenoside R 220Notoginsenoside R2
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