Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Clathrin-IN-1 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 70.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 152.00 | |
25 mg | In stock | $ 272.00 | |
50 mg | In stock | $ 397.00 | |
100 mg | In stock | $ 589.00 | |
500 mg | In stock | $ 1,280.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 113.00 |
Description | Clathrin-IN-1 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research. |
In vitro | Clathrin-IN-1 did not impair clathrin recruitment to the spindle but disrupted its function once stationed there. Clathrin-IN-1 trapped HeLa cells in metaphase through loss of mitotic spindle integrity and activation of the spindle assembly checkpoint, phenocopying clathrin depletion and aurora A kinase inhibition[1]. |
Molecular Weight | 473.36 |
Formula | C20H13BrN2O3S2 |
CAS No. | 1332879-52-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (95.07 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Clathrin-IN-1 1332879-52-3 Microbiology/Virology Proteases/Proteasome HIV Protease Inhibitor vesicle terminal endocytosis domain synaptic amphiphysin clathrin inhibit HIV Pitstop2 Human immunodeficiency virus inhibitor