Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DOCK2-IN-1, an analogue of CPYPP, effectively inhibits DOCK2 (IC50 = 19.1 μM) by reversibly binding to its DHR-2 domain, thereby hindering its catalytic function. This compound obstructs the activation of Rac in lymphocytes, triggered either by chemokine or antigen receptors. Consequently, DOCK2-IN-1 markedly reduces chemotactic responses and T cell activation [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 613.00 | |
50 mg | 6-8 weeks | $ 797.00 | |
100 mg | 6-8 weeks | $ 1,210.00 |
Description | DOCK2-IN-1, an analogue of CPYPP, effectively inhibits DOCK2 (IC50 = 19.1 μM) by reversibly binding to its DHR-2 domain, thereby hindering its catalytic function. This compound obstructs the activation of Rac in lymphocytes, triggered either by chemokine or antigen receptors. Consequently, DOCK2-IN-1 markedly reduces chemotactic responses and T cell activation [1]. |
Molecular Weight | 298.72 |
Formula | C16H11ClN2O2 |
CAS No. | 4590-86-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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DOCK2-IN-1 4590-86-7 inhibitor inhibit